Friday, June 14, 2013

Myositis Outcomes from NINDS

The DM Disease Activity Collaborative Study Group, and later the International Myositis Outcome Assessment Collaborative Study Group recommended development of outcome measures in all forms of IIM  - Idiopathic Inflammatory Myopathies -  in adults and children, and coordination and facilitation of clinical trials in adult and juvenile myositis. 

The main reason stopping this group from undertaking large multi-center trials in myositis is the lack of validated disease activity and damage indices. 
 For this reason, the first in a series of two workshops were held to address the following: 
1. Use of the core set of outcome measures recently identified to develop a myositis disease activity index, a preliminary definition of improvement, and damage index, and 
2. to develop consensus on issues related to the general conduct of clinical trials, extend of improvement and damage, development of inclusion and exclusion criteria and appropriate therapy, and recommendations in regard to the trial duration, dropout criteria, safety assessment, and post-trial evaluations. NINDS 2001

Since this was written things have progressed more on this soon. (Sorry, my research is slow)



1 comment:

  1. Please continue to write more because it’s unusual that someone has something interesting to say about this. Will be waiting for more…

    ReplyDelete

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